AI Product Strategy · Healthcare Research · Systems Engineering

I sit at the intersection of research rigor, technical depth, and product strategy — that combination is rare.

Most AI product leaders come from design, engineering, or business. My path ran through clinical research, population health analytics, and hands-on AI systems engineering. That background shapes everything about how I approach AI products: methodically, with an eye toward governance, and with the operator instincts to know what actually ships.

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Sam Meske
AI product strategy systems engineering research

As a naturally curious researcher and problem solver, I've led research and program development, built products, and shipped AI integrations that streamline workflows and improve outcomes. My goal: empower teams to use data + AI to solve real-world problems.

The career narrative

This is the one section meant to be read, not scanned.

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Research foundation → operations & analytics → AI product strategy & systems engineering.

I started in life sciences — B.S. in Human Biology at Duquesne, M.S. in Exercise Science at Bloomsburg where my thesis work involved EMG signal analysis across resistance training conditions. That sounds far from AI product strategy, but it built something essential: a deep respect for research methodology, measurement validity, and what it actually means to draw defensible conclusions from data. I learned to design studies, run statistical analyses, and communicate findings. That foundation has never left me.

From there I moved into healthcare operations and clinical research management at Main Line Health — eventually as Project Manager on a Phase III investigator-initiated IND trial, coordinating FDA submissions, managing research staff, and overseeing a portfolio of seventeen resident research projects simultaneously. I added an MBA at night during this period to understand the organizational and strategic layer, not just the operational one. By the time I joined Breastcancer.org in 2022, I could hold a rigorous conversation about study design, budget management, and product prioritization in the same meeting — and increasingly, about what AI could and couldn't safely do inside a patient-facing organization.

At Breastcancer.org I came in as Associate Director of Research — directing the annual patient research program, building analytics infrastructure in AWS, designing survey instruments, and producing the quantitative reporting that feeds board strategy. But the role expanded, and so did the work. I started leading product discovery for AI-enabled digital health tools: defining MVPs, establishing governance guardrails, facilitating alignment between technology, content, and medical review teams, and building the systems that would actually make AI safe to deploy in a context where patients are making treatment decisions. Somewhere in that process I went from planning AI systems to building them — production agents, agentic pipelines, parallel orchestration workflows, MCP integrations. I now do both, and I think that's the point.

What this looks like in practice

The combination shows up in consistent patterns.

Background at a glance

Career timeline.

2014
B.S. Human Biology — Duquesne University
2014—2016
Graduate Research & Teaching Assistant — Bloomsburg University
2016
M.S. Exercise Science — Bloomsburg University
2017—2019
Program Coordinator, Concussion Research Institute — Bloomsburg University
2019—2021
Research Assistant & Project Manager (Phase III IND) — Main Line Health
2020
MBA — Bloomsburg University
2021—2022
Department Business Manager, OB/GYN — Main Line Health
2022
Certificate in Full Stack Software Engineering — University of Pennsylvania
2022—Present
Associate Director of Research + expanded product strategy & AI innovation — Breastcancer.org

What I'm looking for next

Personal direction and fit.

I'm actively exploring Director and Senior PM roles in AI product, digital health, and innovation strategy — particularly at organizations where the work is genuinely consequential and where someone who can hold both the research rigor and the technical implementation simultaneously is an asset rather than an edge case.

I'm drawn to organizations building AI products where safety and trust are real constraints, not marketing language. Healthcare, clinical decision support, regulated industries, mission-driven orgs. Places where “move fast and fix it later” isn't an option and where thoughtful product governance is a competitive advantage.

If you're evaluating whether my background fits a role you're hiring for, the case studies on this site will tell you more than a resume. They show how I think, what I build, and the tradeoffs I navigate — not just what I've done.

Publications

Recent/current research plus selected publications, works in preparation, and abstracts.

View publications list
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Google Scholar profile and a curated list of accepted, in-prep, and abstract publications.

Publications (accepted)
  • Weiss, M, Hibbs, J, Buckley, M…Meske, S et al. (2021) A Coala-T survey of breast cancer patients use of cannabis before, during and after treatment. Cancer. CNCR-21-0925.R1
  • Beaupre, J, Meske, S, & Buckley, M. (2021) Athletic Training and Population Health Science. Journal of Athletic Training. Online Ahead of Print.
  • Beaupre, J, Meske, S, & Buckley, M. (2021) Athletic Trainer-reported prevalence of mental health, substance use, and barriers to health in secondary schools. Journal of Athletic Training. Online Ahead of Print.
  • Meske, S, Hazzard, J, Ni, M, Hanson, T, Van Horn, L, & Smith, J. (2018) The Prevalence of Traumatic Brain Injury and On-Campus Service Utilization Among Undergraduate Students. Journal of Head Trauma Rehabilitation. Online Ahead of Print.
  • Mookerjee, S, McMahon, M, & Meske, S. (2017) Influence of joint angle and biceps brachii isometric contraction intensity on electromyographic and mechanomyographic responses. Advances in Skeletal Muscle Function Assessment. 1(2), 21–27.
Publications (in preparation)
  • Gobern, J, Hartwell, L, Meske S, & Carlson, E. (2020) Management of Amniotic Fluid Embolism in a Community Healthcare System: A Case Series. American Journal of Obstetrics & Gynecology.
  • Kennard, K, Ciocca, R, Sabol, J, Carp, N, Meske, S. (2020) Use of PECS II Block in Partial Mastectomy for Improving Postoperative Pain Control and Mitigating Narcotic Use — a Randomized Control Trial. American Journal of Surgery.
  • Hazzard, J, Ni, M, Meske, S, Caccese, Eckner, JT, & Buckley, T. (2019) The effects of sports-related concussion on clinical reaction-time in student-athletes.
  • Buckley, T, Caccese, J, Hazzard, J, Ni, M, Meske, S, & Eckner, JT. (2019) Clinical reaction-time correlation to risk of head injury in student-athletes.
  • Meske, S & Mookerjee, S. (2019) Comparison of EMG responses across handle types during seated row exercise. Journal of Strength and Conditioning Research.
  • Mookerjee, S, McMahon, M, & Meske, S. (2018) EMG amplitude-to-torque ratios in males and females during isokinetic exercise. European Journal of Sports Science.
Abstracts
  • Kennard, K, Buckley, M, Meske, S, Larson, S, et al. Use of PECS II Block in Partial Mastectomy for Improving Postoperative Pain Control and Mitigating Narcotic Use: Initial Results from a Randomized Control Trial. Poster presented to the ASBrS virtual conference, June 2020.
  • Sabato, E, Gobern, J, Meske, S, & Buckley, M. (2020). Racial Disparities in Postpartum Hemorrhage in a Community Hospital: A Retrospective Cohort Analysis. ACOG National Conference.
  • Mezes, C, Meske S, & Gobern, J. (2019). Enhanced Laparoscopic Identification of Peritoneal Endometriosis with Indocyanine Green Contrast: An Educational Video. AAGL International Conference.
  • Mookerjee, S, Meske, S, Beyer, KS, & Drury, D. (2019). Gender Comparisons of Muscle Activation Patterns Across Handle Types During Seated Row Exercise: Medicine & Science in Sports & Exercise. 51(6):143.
  • Meske, S, Hazzard, J, & Ni, M. (2018). Altered state of consciousness in mild traumatic brain injury in relation to utilization of services. Neurology. 91:2.
  • Meske, S, Hazzard Jr., J, Tolan, C, Van Horn, L, Hanson, T, & Smith, J. (2017). Trajectory of recovery from mTBI in an adolescent ice hockey player. IBIA/IPBIS 2nd International Conference on Pediatric Acquired Brain Injury.
  • Meske, S, Hanson, T, Hazzard Jr., J, Van Horn, L, & Smith, J. (2017). Prevalence of traumatic brain injury and utilization of services in an undergraduate population. American Academy of Neurology 4th Annual Sports Concussion Conference.
  • Van Horn, L, Hazzard Jr., J, Smith, P, Meske, S, Hanson, T, & Smith, J. (2017). Residual effects of concussion utilizing a dual-task analysis. American Academy of Neurology 4th Annual Sports Concussion Conference.
  • Van Horn, L, Hazzard Jr., J, Meske, S, Hanson, T, & Smith, J. (2017). Recovery assessment from severe TBI using multiple technologies. 2nd International Conference Pediatric Acquired Brain Injury.
  • Mookerjee, S, Meske, S, & Nocera, V. (2016). Comparison of differences in O2 pulse across upper body resistance exercise. Medicine & Science in Sports & Exercise, 48(5), S278.
  • Nocera, V, Meske, S, & Mookerjee, S. (2015). Gender differences in O2 pulse during single set vs. multiple-set resistance exercise. Mid-Atlantic Regional Chapter of the American College of Sports Medicine 38th Annual Scientific Meeting.
Want to see the work?

The case studies show thinking, structure, governance, and outcomes — more than a resume ever will.

Download resume (PDF)